Scientific cooperation with Cuba in Applied Mathematics


This is the webpage of a cuban and french cooperation project which aim to develop the cooperation in applied mathematics in teaching and research between both countries, to give international visibility to scientific events which hold in Cuba and to set a reference for cubans seeking to pursue their studies abroad. 


Scientific events to be held in Cuba

   16th ICOR 2024 (first annoucement
—   March 5-8, 2024, Universidad de La Habana
—   École EMALCA, November 4-8, 2024, Universidad de La Habana

Next Maestria/Master courses in La Habana by visiting researchers

(Dates to be announced)

—   Hypothesis Testing, Madalina Olteanu (U. Paris Dauphine-PSL)

—   Détection de ruptures (statistiques), Alain Celisse (U. Paris 1) 

—   Signal processing & wavelets, Fabien Navarro (U. Paris 1)

—   Introduction to stochastic calculus, Marelys Crespo (U. Toulouse)

—   Functional Analysis and PDE, Otared Kavian (U. Versailles) & Suney Taste (INRIA Paris)

—   PDEs in biology, Frank Alvarez (U. Paris Dauphine-PSL) & Claudia Fonte (U. Grenoble)

Séminaire Franco-Cubain de mathématique à Paris + visio

Vendredi 14 juin 2024 à 15h à Sorbonne Université  (9h heure de Cuba) salle 1516-3-09 LJLL, couloir 15-16, salle 309 (voici le plan d’accès). 


  Existence and stability in the voltage-conductance equation - Claudia Fonte Sánchez, Inria Grenoble

This talk delves into the non-linear kinetic Voltage-Conductance equation, a crucial mathematical model for understanding neuronal activity. We obtain two key results in a framework suitable for weak interactions. First, we establish the existence of solutions. Second, we prove linear asymptotic exponential stability of the steady state. This stability result builds upon a recent estimate by Dou (2023) and offers a constructive approach. Both results are based in a fundamental way on some ultracontractivity property of the flow associated to the linear of the Voltage-Conductance equation. 

Vendredi 3 mai 2024 à 15h salle D101-102 (bâtiment Maurice Allais - 1er étage), à l'Université Paris Nanterre à 15h heure de Paris (8h30 heure de Cuba) 

   Predicting treatment success in cancer immunotherapy: A causal inference approach  Lizet Sanchez Valdés, Centro de Inmunología Molecular 

Some cancer immunotherapies lead to durable long-term survival in a small percentage of treated patients. Therefore, determining which patients will benefit most from treatment is a major challenge. This study uses a causal inference approach to evaluate predictors of the efficacy of cancer immunotherapies. First, a causal inference model is used to describe the relationship between pretreatment predictors and individual treatment effects. Subsequently, the causal predictive information metric (PCI) is introduced to quantify the information that pretreatment predictors convey about treatment effects. The methodology is applied to identify predictors of treatment success of the Cuban vaccine CIMAvax-EGF in advanced lung cancer. In addition, a two-component Weibull mixture survival model was used to estimate and compare the proportion of long-term survival between selected treated and control patients. Patients classified as good responders according to the selected causal model (PCI > 0.74) had a significantly longer observed survival time compared to the control group. The study underlines the potential of the methodology used for personalized medicine in cancer immunotherapy.

   Field experiments evaluating irradiated Aedes aegypti males for the Sterile Insect Technique - René Gato Armas, Intituto de Medicina Tropical Pedro Pedro Kourí

Dengue fever, a mosquito-borne viral disease, poses a significant public health threat. The sterile insect technique (SIT) is an environmentally friendly method for controlling mosquito populations, that promises to become an alternative to traditional management tools based on pesticides. Field experiments were conducted involving the open release of irradiated male Aedes aegypti mosquitoes in Havana, Cuba. Mark-release-recapture (MRR) trials showed an estimation of dispersion, survival, and mating competitiveness of the sterile mosquitoes under natural conditions, as well as the abundance of wild populations in the study area. The parameters for SIT implementation were set up based on MRR results. A pilot study assessed the efficacy of SIT under real-world conditions in a suburb of Havana, Cuba. The sterile mosquitoes induced a significant degree of sterility in the wild population, leading to a reduction in field populations by approximately 18 weeks. The experiments represent a strong piece of evidence to demonstrate the feasibility of SIT as a tool for Aedes aegypti control. The findings obtained open new perspectives for the development and optimization of this Aedes aegypti control strategy. Advanced studies are ongoing to evaluate the epidemiological impact of SIT on dengue incidence.

Vendredi 8 Décembre 2023,  bât Borel de IHP en salle Olga Ladyjenskaïa (ex salle 01) à 14h30 heure de Paris (8h30 heure de Cuba) 

   Mariano Rodríguez Ricard (U. La Habana)  

   Cristina Chavez Chong (ICIMAF) 

   Gemayqzel Bouza Allende (U. La Habana)

Vendredi 13 Octobre 2023, U. Paris Dauphine-PSL en salle D306, à partir de 15h30 heure de Paris (9h30 heure de Cuba) 

   Limites d'échelle autour du graphe d'Erdös-Renyi  - Josue Corujo Rodriguez (UPEC)

   Problèmes de temps moyen d'arrivée et applications dans le processus de libération du calcium induite par le calcium - Suney Toste (ENS)